Publikationen
Aicher, A., Heeschen, C., Mildner-Rihm, C., Urbich, C., Ihling, C., Technau-Ihling, K., Zeiher, A.M., Dimmeler, S. (2003) Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med, 9:1370-1376.
Acker, T., Diez-Juan, A., Aragones, J., Tjwa, M., Brusselmans, K., Moons, L., Fukumura, D., Moreno-Murciano, M. P., Herbert, J. M., Burger, A., Riedel J, Elvert G, Flamme I, Maxwell PH, Collen D, Dewerchin M, Jain RK, Plate KH, Carmeliet P. (2005). Genetic evidence for a tumor suppressor role of HIF-2alpha. Cancer Cell, 8, 131-141.
Bézard, E., Ferry, S., Mach, U., Stark, H., Leriche, L., Boraud, T., Gross,C., Sokoloff, P. (2003) Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function. Nat Med, 9(6): 762-7.
Bonig, H., Wundes, A., Chang, K.H., Lucas, S., Papayannopoulou, T. (2008) Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab. Blood, 111(7), 3439-41.
Brandts, C.H., Sargin, B., Rode, M., Biermann, C., Lindtner, B., Schwäble, J., Buerger, H., Müller-Tidow, C., Choudhary, C., McMahon, M., Berdel, W.E., Serve, H. (2005) Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation. Cancer Res, 65(21):9643-50.
Choudhary, C., Brandts, C., Schwäble, J., Tickenbrock, L., Sargin, B., Ueker, A., Böhmer, F.D., Berdel, W.E., Müller-Tidow, C., Serve, H. (2007) Activation mechanisms of STAT5 by oncogenic Flt3-ITD. Blood, 110(1):370-4.
Engel, M., Hindie, V., Lopez-Garcia, L.A., Stroba, A., Schaeffer, F., Adrian, I., Imig, J., Idrissova, L., Nastainczyk, W., Zeuzem, S., Alzari, P.M., Hartmann, R.W., Piiper, A., and Biondi, R.M. (2006); Allosteric activation of protein kinase PDK1 with low molecular weight compounds. EMBO J 25(23), 5469-80.
Essmann, C. L., Martinez, E., Geiger, J. C., Zimmer, M., Traut, M. H., Stein, V., Klein, R., and Acker-Palmer, A. (2008). Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nat Neurosci, 11, 1035 – 1043.
Gao, Q., Mezei, G., Nie, Y., Rao, Y., Choi, C.S., Bechmann, I., Leranth, C., Toran-Allerand, D., Priest, C.A., Roberts, J.L., Gao, X.B., Mobbs, C., Shulman, G.I., Diano, S., Horvath, T.L. (2007) Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med, 13(1), 89-94.
Grabbe, C., Dikic, I. (2008) Going global on ubiquitin. Science, 322(5903):872-3.
Kraemer, O., Baus, D., Knauer, S., Stein, S., Jaeger, E., Stauber, R.H., Grez, M., Pfitzner, E and Heinzel, T. (2006) Acetylation of Stat1 modulates NF-kappa B signalling. Genes & Development, 20, 473-485.
Lai, C.L., Gane, E., Liaw, Y.F., Hsu, C.W., Thongsawat, S., Wang, Y., Chen, Y., Heathcote, E.J., Rasenack, J., Di Bisceglie, A.M., Zeuzem, S., Moon, Y.M., Goodman, Z., Chao, G., Brown, N.A. (2007); A comparison of telbivudine and lamivudine in patients with chronic hepatitis B. N Engl J Med 357(25):2576-88.
Liebner, S., Corada, M., Bangsow, T., Babbage, J., Taddei, A., Czupalla, C.J., Reis, M., Felici, A., Wolburg, H., Fruttiger, M., Taketo, M.M., von Melchner, H., Plate, K.H., Gerhardt, H., Dejana, E. (2008) Wnt/beta-catenin signaling controls development of the blood-brain barrier. J Cell Biol., 183(3):409-17.
Llovet, J.M., Ricci, S., Mazzaferro, V., Hilgard, P., Gane, E., Blanc, J.F., de Oliveira, A.C., Santoro, A., Raoul, J.L., Forner, A., Schwartz, M., Porta, C., Zeuzem, S., Bolondi, L., Greten, T.F., Galle, P.R., Seitz, J.F., Borbath, I., Häussinger, D., Giannaris, T., Shan, M., Moscovici, M., Voliotis, D., Bruix, J. (2008); SHARP Investigators Study Group. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359(4):378-90.
Luttun, A.*, Tjwa, M.*, Moons, L., Wu, Y., Angelillo-Scherrer, A., Liao, F., Nagy, J., Hooper, A., Priller, J., De Klerck, B., Compernolle, V., Bohlen, P., Dewerchin, M., Herbert, J., Fava, R., Matthys, P., Carmeliet, G., Collenm D., Dvorak, H., Hicklin, D., Carmeliet, P. (2002) Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt-1 antibody (*equally contributed). Nat Med, 8(8):831-40.
Meyer, C., Schneider, B., Reichel, M., Angermueller, S., Strehl, S., Schnittger, S., Schoch, C., Jansen, M.W., van Dongen, J.J., Pieters, R., Haas, O.A., Dingermann, T., Klingebiel, T., Marschalek, R. (2005). Diagnostic tool for the identification of MLL rearrangements including unknown partner genes. Proc Natl Acad Sci USA, 102:449-54.
Ott, M.G., Schmidt, M., Schwarzwaelder, K., Stein, S., Siler, U., Koehl, U., Glimm, H., Kühlcke, K., Schilz, A., Kunkel, H., Naundorf, S., Brinkmann, A., Deichmann, A., Fischer, M., Ball, C., Pilz, I., Dunbar, C., Du, Y., Jenkins, N.A., Copeland, N.G., Lüthi, U., Hassan, M., Thrasher, A.J., Hoelzer, D., von Kalle, C., Seger, R., Grez, M. (2006) Correction of X-linked Chronic Granulomatous Disease by gene therapy, augmented by insertional activation of MDS/EVI1, PRDM16 or SETBP1. Nat Med, 12, 401-9.
Petrova, T.V., Nykènen, A., Norrman, C., Ivanovm K,I., Andersson, L.C., Haglund, C.,Puolakkainen, P., Wempe, F., von Melchner, H,, Gradwohl, G., Vanharanta, S., Aaltonen, L.A., Saharinen, J., Gentile, M., Clarke, A., Taipale, J., Oliver, G., Alitalo, K. (2008) Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype. Cancer Cell, 13(5):407-19.
Rüster, B., Göttig, S., Ludwig, R.J., Bistrian, R., Müller, S., Seifried, E., Gille, J., Henschler, R. (2006) Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells. Blood, 108(12):3938-44.
Sargin, B., Choudhary, C., Crosetto, N., Schmidt, M.H., Grundler, R., Rensinghoff, M., Thiessen, C., Tickenbrock, L., Schwäble, J., Brandts, C., August, B., Koschmieder, S., Bandi, S.R., Duyster, J., Berdel, W.E., Müller-Tidow, C., Dikic, I., Serve, H. (2007) Flt3-dependent transformation by inactivating c-Cbl mutations in AML. Blood, 110(3):1004-12.
Skarnes, W.C., von Melchner, H., Wurst, W., Hicks, G., Nord, A.S., Cox, T., Young, S.G., Ruiz, P., Soriano, P., Tessier-Lavigne, M., Conklin, B.R., Stanford, W.L., Rossant, J.( 2004) International Gene Trap Consortium. A public gene trap resource for mouse functional genomics. Nat Genet, 36(6):543-4.
Schachinger, V., Erbs, S., Elsasser, A., Haberbosch, W., Hambrecht, R., Holschermann, H., Yu, J., Corti, R., Mathey, D. G., Hamm, C. W., Suselbeck, T., Assmus, B., Tonn, T., Dimmeler, S. and Zeiher, A. M. (2006) Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med, 355:1210-21.
Schmuker, M., Schneider, G. (2007) Processing and classification of chemical data inspired by insect olfaction. Proc Natl Acad Sci USA, 104: 20285-9.
Schreiner, P., Chen, X., Husnjak, K., Randles, L., Zhang., N, Elsasser, S., Finley, D., Dikic, I., Walters KJ, Groll M. (2008) Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature, 453(7194):548-52.
Strebhardt, K., Ullrich, A. (2008) Paul Ehrlich's magic bullet concept: 100 years of progress. Nat. Rev. Cancer 8,473-480.
Strebhardt, K., Ullrich, A. (2006) Targeting polo-like kinase 1 for cancer therapy. Nat. Rev. Cancer 6, 321-330.
von Knethen, A., Soller, M., Tzieply, N., Weigert, A., Johann, A. M., Jennewein, C., Kohl, R. and Brune, B. (2007) PPARgamma1 attenuates cytosol to membrane translocation of PKCalpha to desensitize monocytes/ macrophages. J Cell Biol, 176: 681-94.
Wei, Y., Liu, S., Lausen, J., Cho, S., Biris, N., Kobayashi, N., Wei, Y., Yokoyama, S., Werner, M.H. (2007) A TAF4-homology domain from the corepressor Eight Twenty-one (ETO) is a docking platform for positive and negative regulators of transcription. Nat Struct Mol Biol, 14(7), 653-661.
Weigert, A., Johann, A. M., von Knethen, A., Schmidt, H., Geisslinger, G. and Brune, B. (2006) Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate. Blood, 108: 1635-42.
Zheng, X., Beissert, T., Kukoc-Zivojnov, N., Puccetti, E., Altschmied, J., Strolz, C., Boehrer, S., Gul, H., Schneider, O., Ottmann, O.G., Hoelzer, D., Henschler, R., Ruthardt, M. (2004) Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells. Blood, 103(9):3535-43.
Erstellt von: S. Ohm, erstellt am: 03.01.2011, zuletzt geändert: 17.01.2011










