Scientists

2021/2022

MS Student
Tobias Bexte

Department of Pediatric and Adolescent Medicine, Experimental Immunology
Supervisor: Prof. Dr. Evelyn Ullrich

Project: Entwicklung einer neuen CRISPR/Cas9-basierten NK-Zell-Therapie zur Behandlung unterschiedlicher Krebserkrankungen

MD Student
Daniel Dadra
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Institute for Experimental Cancer Research in Pediatrics
Supervisor: Dr. Sjoerd van Wijk

Project: Understanding the role of USP22 in MET signalling in rhabdomyosarcoma cell lines

MD Student
Abdallah El Sheikha

Georg-Speyer-Haus Institute for Tumor Biology and Experimental Therapy
Supervisor: Dr. Lisa Sevenich

Project: Auswirkungen der Standardtherapie auf die immunologische Mikroumgebung von Hirnmetastasen und Perspektiven zur Entwicklung neuartiger adjuvanter Therapien

MD Student
Lena Groger

Department of Medicine 2, Hematology/Oncology
Supervisor: PD Dr. Frank Schnütgen

Project: Regulation des pro-apoptotischen Effektorproteins BAX in AML-Zellen nach Venetoclax-Exposition

MD Student
Jessica Rüger

Dr. Senckenberg Institute of Pathology
Supervisor: Prof. Dr. Peter Wild / Dr. Nadine Flinner

Project: Quantitative Determination of NASH Score Components

MD Student
Margaux Schweigert

Institute for Transfusion Medicine and Immunohematology/ DRK Blood Donor Service
Supervisor: Prof. Dr. Halvard Bönig

Project: In vivo Expansion, Phänotypenwandel und Entwicklung von Seneszenz CAR-modifizierter T-Zellen unter kontinuierlicher Antigenexposition

MD Student
Karla Wolf

Department of Medicine 1
Supervisor: Dr. Guido Plotz

Project: Untersuchungen zur Pathogenität unklarer MLH1-Varianten bei Verdacht auf Lynch-Syndrom

2019/2020 - Alumni

MD Student
Ufuk Erdogdu

Institute for Experimental Cancer Research in Pediatrics
Supervisor: Prof. Simone Fulda

Project: Combined inhibition of BET and the antiapoptotic protein BCL-xL as a new treatment strategy for rhabdomyosarcoma

MD Student
Carmen Franiczek

Dr. Senckenberg Institute for Neurooncology
Supervisor: Prof. Joachim Steinbach

Project: Relevance of the cystine/glutamate transporter xCT in glioma cells

MD Student
Veronika Gebel

Institute for Experimental Immunology, Department of Pediatric and Adolescent Medicine
Supervisor: Prof. Evelyn Ullrich

Project: Optimization of viral transduction of CD19-CAR-NK cells for therapy of acute lymphatic leukemia

MD Student
Lea Graafen

Institute for Experimental Immunology, Department of Pediatric and Adolescent Medicine
Supervisor: Prof. Evelyn Ullrich

Project: Functionality of natural killer cells in patients with Ataxia telangiectasia

MD Student
Lea Hermann

Department of Medicine II, Hematology/Oncology
Supervisor: Prof. Christian Brandts

Project: Characterization of the kinase-dependent content of autophagosomes in FLT3-ITD AML by proteomics

MD Student
Sofia Krujatz

Department of Medicine II, Hematology/Oncology
Supervisor: Prof. Hubert Serve

Project: CRIPSR/Cas9-based identification of hypoxia-specific vulnerabilities in AML

MD Student
Anastasia Parmon

Department of Medicine II, Hematology/Oncology
Supervisor: Dr. Frank Schnütgen

Project: Investigation of the mechanisms of the protein IREB2 in AML cells

MD Student
Marius Winkler

Institute for Experimental Cancer Research in Pediatrics
Supervisor: Prof. Simone Fulda

Project: Investigation of cell death mechanisms induced by combined inhibition of oncogenic RAS/MEK/ERK signaling pathway and antiapoptotic MCL-1 protein in rhabdomyosarcoma

Clinician Scientist
Dr. med. Anjali Cremer

Department of Medicine II, Hematology/Oncology
Max Eder Junior Research Group

Project: Inflammatory signaling via activation of NF-κB is a resistance mechanism to targeted therapy in acute myeloid leukemia (AML)

Clinician Scientist
Dr. med. Katharina Filipski

Neurological Institute (Edinger Institute)
AG Harter

Project: Deciphering the cellular composition of diffuse glioma by use of epigenetic traits

Clinician Scientist
Dr. med. Christian Issing

Department for Ear-, Nose-, Throat Medicine and Georg-Speyer-Haus Institute for Tumor Biology and Experimental Therapy
AG Farin

Project: Patient-derived tumor organoids from head and neck squamous cell carcinoma as a co-clinical research platform

Clinician Scientist
Dr. med. Florestan Koll

Department of Urology and Dr. Senckenberg Institute of Pathology
AG Wild

Project: Molecular and histological subtyping of muscle-invasive bladder cancer

Clinician Scientist
Dr. med. Sebastian Koschade

Department of Medicine II, Hematology/Oncology
AG Brandts

Project: Dissecting the autophagic degradome in FLT3-ITD+ acute myeloid leukemia

Clinician Scientist
PD Dr. med. Henriette Rudolph

Department of Pediatric and Adolescent Medicine

Project: Identification of CNS prone Chimeric Antigen Receptor (CAR) T-Cells in human models of the Blood-Cerebrospinal fluid barrier and the Blood-Brain-Barrier

Clinician Scientist
Dr. med. Katharina Wenger-Alakmeh

Institute of Neuroradiology
AG Hattingen

Project: MR-spectroscopic in vivo metabolic profiling – a novel “omic” in the multi-omics assessment of diffuse large B-cell lymphoma

Clinician Scientist
Dr. med. Pia Zeiner

Dr. Senckenberg Institute for Neurooncology
AG Steinbach

Project: Interaction between glioma-associated microglia/macrophages and tumor cells in the context of targeted cancer therapies and immunotherapies

Advanced Clinician Scientist 
Dr. med. Anna-Luisa Luger

Dr. Senckenberg Institute of Neurooncology

Project: Redox stress in the glioblastoma microenvironment – implications for therapy resistance and new treatment approaches

Advanced Clinician Scientist 
Dr. med. Patrizia Malkomes

Department of Visceral Surgery

Project: The role of Transglutaminase 2 in tumor progression and its significance as prognostic marker and therapeutic target

Advanced Clinician Scientist 
PD Dr. med. Eva Rettinger

Department of Pediatric and Adolescent Medicine

Project: HER2/ErbB2-chimeric antigen receptor (CAR)-modified lymphocyte-centered immunotherapies for the clinical use in relapsed/refractory (r/r) childhood soft tissue sarcoma (STS)

Junior Group Leader
Dr. Nadine Flinner

Dr. Senckenberg Institute for Pathology

Research Focus: Digital Pathology

The Mildred Scheel Career Center Frankfurt is funded by the German Cancer Aid.