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The Mildred Scheel Career Center Frankfurt-Marburg is seeking a motivated Junior Group Leader to join the research community in Frankfurt, starting from the earliest possible date. 

Junior Group Leader – Immunopathogenesis of B-cell malignancies

fulltime | limited contract until December 31^st, 2027 | announcement no. 2206313

The Mildred Scheel Career Center (Mildred-Scheel-Nachwuchszentrum, MSNZ) Frankfurt-Marburg is a joint institution of the Faculty of Medicine of the Goethe University, the Universitätsmedizin Frankfurt, the University Cancer Center (UCT) Frankfurt-Marburg and the Frankfurt Cancer Institute (FCI). The MSNZ Frankfurt-Marburg is one of five sites in Germany funded by the German Cancer Aid within the framework of the research program “Mildred-Scheel-Nachwuchszentren”. The MSNZ offers an excellence program for Medical Scientists (scientists with a life science background or physicians working exclusively in science) pursuing a long-term perspective in academic medicine. The MSNZ funds are intended for the scientist’s own position and for his or her own scientific projects to support the development into an independent group leader.

Project description:

The MSNZ Frankfurt-Marburg and the Department of Hematology and Oncology (Prof. Dr. med. Thomas Oellerich) aim to strengthen their research activities in the field of immunological mechanisms of B-cell lymphomagenesis. Integrated into the Department of Hematology and Oncology and the translational cancer research program of the Frankfurt Cancer Institute (FCI), the German Cancer Consortium (DKTK) and the UCT Frankfurt-Marburg, the junior group will focus on the areas of molecular and immunological pathogenesis and targeted therapeutics of B-cell Lymphoma. Numerous omics-technologies and preclinical models are available to support the junior group and can be included in the research proposal. Further support is provided by the technological platforms and staff scientists of the FCI (drug screening, organoids, animal models, immunomonitoring), as well as the expertise of the UCT Biobank for patient samples and annotated clinical data. 

Your profile:

• University degree and PhD or MD or MD-PhD in life sciences or a related field with outstanding scientific credentials and postdoc experience
• Extensive expertise in both basic and translational cancer biology, with a deep understanding of B-cell lymphoma development, disease pathogenesis, and tumor immunology acquired through research training in internationally recognized institutions
• Strong methodological expertise in immunology, advanced mouse models, CRISPR screening, and integrative functional proteomics and transcriptomics
• Publications in high-ranking international scientific journals
• Experience with obtaining third party funding
• Research expertise in one of the topics relevant for the mission of the FCI, the UCT and the DKTK
• A competitive research proposal within the aims of the FCI, the UCT and the DKTK
• Strong interest in promoting your own career and scientific independence
• High level of motivation and communication skills
• Due to legal regulations, valid proof of measles immunity / measles vaccination is required.

Our offer:

• In addition to an attractive salary based on a collective agreement (TV-GU, E14) with an annual special payment, you benefit from long-term security through company pension schemes
• Part-time employment is possible, we offer childcare in our daycare center (if you have any questions, please contact UKF-Familienservice), child care during holidays
• Free public transport in all Hessen (Free State Ticket Hessen)
• Excellent environment to establish an independent research group
• Integration into the FCI, the UCT and the DKTK
• Access to scientific infrastructure and established preclinical models
• Excellent basic research linked to translational and clinical aspects
• Participation in training and qualification programs of the MSNZ
• A diverse and challenging task in an outstanding scientific and international environment
• Our university hospital campus offers a modern cafeteria, various cafés, and green spaces to relax in.
• Regular online and face-to-face courses on nutrition, relaxation, sports and exercise for employees

We welcome applications from candidates of all genders. Women are currently underrepresented in these positions at Universitätsmedizin Frankfurt. Therefore, applications from women are especially encouraged. Applicants with severe disabilities will be given preferential consideration in case of equal personal and professional qualification.

Application

Please use exclusively the application form provided below and submit your request electronically, stating the announcement number and a possible starting date, together with your CV, a cover letter and your relevant certificates, until February 11, 2026 via the career portal of the University Hospital Frankfurt.

Download – Application Form Junior Group Leader

Selection process

After reviewing the application documents, the selection committee will invite promising candidates to a scientific colloquium to present their project proposal and scientific concept.

Are you interested? We are looking forward to your application!

For questions concerning the application, please contact Prof. Dr. Christian Brandts (Spokesperson MSNZ; phone +49 (0)69 6301-87334) and Dr. Tinka Haydn (Coordination MSNZ; phone +49 (0)69 6301-7251, email: msnz@unimedizin-ffm.de).

Further information on the FCI and UCT and their research program can be found at http://fci.health and www.uct-frankfurt.de/forschung. An overview of the MSNZ is available at www.msnz-frankfurt.com. Information on research of the Department of Hematology and Oncology can be found here: https://lymphoma-leukemia-research-frankfurt.de